Pauka L-Tyrosine
l-tyrosine
hoʻolauna pōkole
ʻO Tyrosine (i hoʻopōkole ʻia e like me Tyr a i ʻole Y) a i ʻole 4-hydroxyphenylalanine kekahi o nā waikawa amino 22 i hoʻohana ʻia e nā cell e synthesize i nā protein. Hiki ke hoʻohana ʻia e synthesize i nā protein i loko o nā cell, me nā codons UAC a me UAU. He waikawa amino koʻikoʻi ʻole ia e loaʻa ana nā hui ʻaoʻao polar a hiki ke synthesized e ke kino kanaka. Loaʻa ka huaʻōlelo 'tyrosine' mai ka ʻōlelo Helene tyros, ʻo ia hoʻi ka tīhi. I ka hoʻomaka ʻana o ke kenekulia 19, ua ʻike mua ʻia e ka chemist Kelemania ʻo Eustus von Libich i loko o ka tīhi casein, a i ka wā e hoʻohana ʻia ai ma ke ʻano he hui hana a ʻaoʻao paha, ua kapa ʻia ʻo tyrosine.
hana
Ma waho aʻe o ka lilo ʻana i amino acid protein, he kuleana kūikawā ko tyrosine i ka hoʻoili ʻana i nā hōʻailona i loko o nā protein ma o ka hilinaʻi ʻana i nā hui hana phenolic. ʻO kāna hana he mea loaʻa no nā hui phosphate i hoʻoili ʻia e nā kinases protein (nā mea i kapa ʻia ʻo tyrosine kinase receptors), ʻoiai ʻo ka phosphorylation o nā hui hydroxyl e hoʻololi i ka hana o ka protein target.
He kuleana koʻikoʻi ko Tyrosine i ka photosynthesis, e lawelawe ana ma ke ʻano he mea hoʻolako electron i ka hopena hōʻemi o ka chlorophyll oxidized i loko o nā chloroplasts (Photosystem II), deprotonation o nā hui OH phenolic, a me ka hōʻemi hope loa e nā hui manganese ʻehā ma Photosystem II.
Nā kumu meaʻai
Hiki ke hoʻopili ʻia ʻo Tyrosine mai ka phenylalanine i loko o ke kino a hiki ke loaʻa i loko o nā meaʻai protein kiʻekiʻe e like me ka moa, ka pelehū, ka iʻa, ka waiū, ka yogurt, ka tīhi, ka tīhi, nā pīnati, nā ʻalemona, nā hua paukena, ka sesame, ka soybeans, nā pīni lima, nā avocados, a me ka maiʻa.
He ʻakika amino koʻikoʻi ʻole ka L-tyrosine a ʻo ia kekahi o nā mea nui i ke ala metabolism methionine. Loaʻa ia i nā meaola a he kuleana koʻikoʻi kāna i nā kaʻina hana olaola he nui.
He ʻāpana ʻo L-tyrosine o nā protein a komo i ke kaʻina hana o nā protein. He mea hoʻomākaukau nō hoʻi ia no nā mea bioactive like ʻole, me nā neurotransmitters catecholamine e like me ka dopamine, norepinephrine, a me ka adrenaline, a me nā hormones thyroid a me ka melanin.
Eia kekahi, pili pū ʻo L-tyrosine i ka synthesis o nā molekala olaola koʻikoʻi ma o kahi moʻo o nā enzymes i loko o ke kino, e like me ka tyrosine kinase a me ka tyrosine hydroxylase, i komo i nā ala hōʻailona kinase a me ka hoʻoponopono physiological.
Hiki ke loaʻa ka lawe ʻana o ka L-tyrosine ma o ka ʻai ʻana, me nā kumu meaʻai he nui e like me nā nati, nā hua, ka ʻiʻo, ka iʻa, a me nā huahana waiū. Eia kekahi, hiki ke hoʻololi ʻia ka L-tyrosine mai kahi waikawa amino ʻē aʻe, ʻo ka phenylalanine, ma o ke ala hana tyrosine i loko o ke kino.
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