Kolina klorida
He hui organik ka Choline chloride me ke ʻano kemika C5H14ClNO. He kristal hygroscopic keʻokeʻo ia, ʻaʻohe ala, a he ʻala iʻa. Hehi 305 ℃. ʻO kahi hopena wai 10% me ka pH 5-6 he paʻa ʻole i ka hopena alkaline. He maʻalahi ka hoʻoheheʻe ʻia o kēia huahana i ka wai a me ka ethanol, akā ʻaʻole i loko o ka ether, petroleum ether, benzene, a me ke kalapona disulfide. Haʻahaʻa ka ʻawahia, LD50 (ʻiole, waha) 3400 mg/kg. Hoʻohana ʻia no ka mālama ʻana i ke akepaʻa momona a me ka cirrhosis. Hoʻohana pū ʻia ma ke ʻano he mea hoʻohui hānai no nā manu a me nā holoholona, hiki iā ia ke hoʻoulu i nā ovaries e hana i nā hua hou aʻe, nā ʻōpala, a loaʻa ke kaumaha i nā manu, nā iʻa, a me nā holoholona ʻē aʻe.
Hoʻohana:nā lāʻau lapaʻau, nā kemika, nā huahana hānai, nā huahana mahiʻai, nā mea hoʻohui meaʻai
Ma ke ʻano he mea hoʻohui hānai, loaʻa i ka choline chloride nā hopena physiological penei:Hiki iā ia ke pale i ka hōʻiliʻili ʻana o ka momona a me ka degeneration o nā ʻiʻo i loko o ke akepaʻa a me nā puʻupaʻa; Hiki ke hoʻoulu i ka hui hou ʻana o nā waikawa amino; Hiki iā ia ke hoʻomaikaʻi i ka nui o ka hoʻohana ʻana o nā waikawa amino, ʻoiai ka methionine amino acid koʻikoʻi, i loko o ke kino. Ma Iapana, 98% o ka choline chloride i hoʻohana ʻia ma ke ʻano he mea hoʻohui hānai no nā holoholona e like me nā moa, nā puaʻa, nā pipi bipi, a me nā iʻa a me nā ʻōpae. Hoʻoponopono ʻia ka hapa nui o lākou i pauka, a ʻo ke ʻano hoʻomākaukau no ka pauka 50% ʻo ia ka hoʻohui mua ʻana i kahi excipient nui kūpono i loko o kahi mea hui, a laila e hoʻohui i kahi hopena wai choline chloride, i hui ʻia a maloʻo. Hoʻohui pū ʻia kekahi mau pauka huahana me nā huaora, nā minelala, nā lāʻau lapaʻau, a me nā mea ʻē aʻe. ʻO Choline chloride kahi lāʻau huaora B i hoʻohana ʻia no nā maʻi e like me ka hepatitis, ka degradation o ke akepaʻa, ka cirrhosis mua, a me ka anemia pernicious.
ʻO Choline kahi ʻāpana koʻikoʻi o ka lecithin, nona ke kuleana koʻikoʻi i ka mālama ʻana i ke ʻano maʻamau a me ka hana o nā membrane cell, a me ka metabolism lipid, a hiki ke pale i ka waiho ʻana o ka momona o ke ake.
He mea nui nō hoʻi ʻo Choline i ka hana ʻana o ka neurotransmitter acetylcholine, a hana pū ia ma ke ʻano he mea hāʻawi methyl i ka hana ʻana o ka methionine.
Hoʻohana ʻia ka Choline chloride no ka hoʻoulu ʻana i ka ulu ʻana a me ka nele o ka choline.
Aia i loko o ka meaʻai kahi nui o ka choline, hiki ke hana ʻia e ke akepaʻa i loko o ke kino, no laila ʻaʻole ia e hoʻopilikia i ka nele o ka choline. Eia nō naʻe, ʻo nā moa ʻuala, ʻoi aku hoʻi nā moa, he nui ka makemake no ka choline a he haʻahaʻa ka synthesis. Inā ʻaʻole i hoʻohui ʻia ka meaʻai a i ʻole hānai ʻia me ka meaʻai haʻahaʻa choline (e like me ka kulina) no ka manawa lōʻihi, he maʻalahi ke hoʻopilikia i ka nele.
Ke loaʻa i nā manu hānai nā maʻi akepaʻa a ʻaʻohe lawa o ka wikamina B2 a me ka waikawa folic i kā lākou meaʻai, hiki nō hoʻi ke kumu o ka nele o ka choline. Ke loaʻa ka nele o ka choline, hōʻike nā puaʻa i ka ulu lohi, ka paʻakikī o nā hono a me ka dyskinesia, ka waiho ʻana o ka momona o ke akepaʻa, a me ka emi ʻana o ka hana hānau. Hōʻike nā manu i ka ulu lohi, ka tibia pōkole a mānoanoa, kahi maʻalahi i ka hemo ʻana o ke aʻalolo, ka maʻi akepaʻa momona, a me ka emi ʻana o ka hana hua.
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