Ola Kino Metabolic a me ka Hoʻemi ʻana i ke Koko

Me ka hiki ke kōkua i ka mālama ʻana i nā pae kō koko olakino, a hoʻomaikaʻi i ka ʻike o ka insulin, ua ʻike nui ʻia ka pauka berberine ma ka ʻoihana honua o kēlā me kēia lā a me nā mea hoʻohui meaʻai. Eia kekahi, ma o ka hoʻoulu ʻana iā AMPK, hoʻonui ka pauka berberine i ka lawe ʻana o ka glucose e nā ʻiʻo, noho i ka hana glucose i loko o ke ake, a hoʻoponopono i ka hana o nā enzymes e pili ana i ka metabolism glucose, e like me dipeptidyl peptidase-4 (DPP-4) - e hoʻonui ana i nā pae GLP-1 ma 40-50% e hoʻonui i ka hopena incretin. E like me ka hōʻike ʻana o ka noiʻi ʻepekema, hiki i ka mahele lāʻau o 500mg berberine ke hōʻemi i ke kō koko hoʻokē ʻai ma 1.5-2.0mmol/L a me ka hemoglobin glycated (HbA1c) ma 0.8-1.2% i nā poʻe me nā pae kō koko kiʻekiʻe. Eia kekahi, kākoʻo pū ka berberine i ka hoʻokele kaumaha ma o ka hoʻolaha ʻana i ka oxidation fatty acid a me ka pale ʻana i ka ulu ʻana o nā ʻāpana momona, ʻoi aku ka nānā ʻana i ka momona ʻōpū i ka wā e hui pū ʻia me kahi nohona olakino.

Kākoʻo Ola Kino o ka Pūnaʻau

Ma o ka hoʻoponopono ʻana i ka metabolism lipid a me ka mālama ʻana i nā pae cholesterol olakino, hana maikaʻi ʻo berberine i ke kākoʻo ʻana i ke olakino cardiovascular. Hoʻohaʻahaʻa ʻo Berberine i nā pae LDL ("cholesterol" maikaʻi ʻole) a me triglyceride me ka hoʻonui ʻana i ka HDL ("cholesterol" maikaʻi), e hōʻemi ana i ka pilikia o ka hōʻiliʻili ʻana o ka plaque i loko o nā kīʻaha koko. Eia kekahi, hoʻopuka ʻo berberine i nā hopena hypotensive iki, e kōkua ana i ka mālama ʻana i nā pae koko olakino, a kākoʻo i ka hana o ka puʻuwai ma ka hōʻemi ʻana i ka mumū i loko o nā ʻiʻo puʻuwai a me ka hoʻoponopono ʻana i ka rhythm o ka puʻuwai.

Kākoʻo Ola Kino a me ka ʻōpū

Ua hōʻike ʻo Bererine i ka hopena koʻikoʻi i ka hana antimicrobial e kūʻē i nā bacteria ʻino o ka ʻōpū (e like me H. pylori), nā fungi, nā parasites, a me nā virus—e kūlike me kāna ʻano antimicrobial ākea e komo pū ana me nā bacteria gram-positive, nā bacteria gram-negative, nā virus influenza like ʻole, a me nā fungi. I kēia manawa, hiki i ka berberine ke kākoʻo i ka ulu ʻana o ka microbiota ʻōpū maikaʻi, e hoʻonui ana i ka hapa o nā bacteria maikaʻi e 20-30% a me ka hoʻolaha ʻana i ka hana ʻana o nā waikawa momona pōkole.

Nā hopena antimicrobial a me anti-inflammatory

ʻAʻole i kaupalena ʻia ka hana a Bererine i ke olakino o ka ʻōpū, he kūpono hoʻi ia e kūʻē i nā ʻano pathogens like ʻole, me nā bacteria (e like me Staphylococcus aureus, E. coli), fungi (e like me Candida albicans), a me nā virus. Hoʻopili ʻia kāna hana anti-inflammatory ma ke kāohi ʻana iā NF-κB a me nā ala pro-inflammatory ʻē aʻe, e hōʻemi ana i ka mumū haʻahaʻa mau loa e pili ana i nā maʻi metabolic, ka ʻeha o nā hono, a me ka ʻelemakule ʻana o ka ʻili.